How much tirzepatide to inject — and what that means for what you pay

What the licensed schedule actually looks like, and what the trial data say about higher doses

Tirzepatide is licensed in the UK under the brand name Mounjaro, manufactured by Eli Lilly. The six available strengths are 2.5, 5, 7.5, 10, 12.5 and 15 mg, each delivered once a week via a pre-filled KwikPen. Treatment opens at 2.5 mg (a tolerability step whose job is to let your system adjust, not to produce meaningful weight loss) before the prescriber considers moving you up, typically in roughly four-week intervals. According to NICE's appraisal of tirzepatide (TA1026), if less than 5% of body weight is lost after six months at the highest tolerated dose, continuing treatment is reviewed.

The trial evidence is striking at higher doses. In the SURMOUNT-1 study, published in the New England Journal of Medicine, adults on 15 mg tirzepatide lost around 20–21% of body weight on average over 72 weeks alongside a reduced-calorie diet and increased activity. Results at lower maintenance doses were still clinically meaningful, just less pronounced. That dose-response relationship is relevant to pricing: if you want to understand what tirzepatide injections cost at each strength, it is worth knowing that what you inject each week and what you pay are genuinely linked.

For a fuller picture of how private pricing varies by dose, our guide to tirzepatide injection prices explains the current market context in more detail.

Why the headline price you see elsewhere may not reflect what you actually spend

Private weight-loss treatment in the UK is generally priced per pen, per month, by dose and provider. Since Eli Lilly raised Mounjaro's UK list price in September 2025, reported private market prices have ranged from roughly £149 to £375 per month depending on the strength and where you buy, figures that are widely quoted but worth treating as a range, not a guarantee. Many headline prices are for the starter dose only. Once your prescriber moves you to a higher strength, the monthly figure changes.

That gap between advertised and actual cost is widened further when you account for what some providers charge separately: consultation fees, prescription fees, delivery charges and any follow-up clinical reviews. Someone who budgets based on a low introductory price can find the real ongoing cost looks quite different by month three. The full breakdown of tirzepatide costs on this site walks through each of those components so nothing comes as a surprise.

Payday timing, public holidays, and Monday order cut-offs matter too, and our tirzepatide price guide covers how these factors can affect your cost timing, so it is worth reading if you are planning ahead.

Where nume sits in this, and why we are not trying to be the cheapest

Our pricing is deliberately not the lowest on the market. That is a choice, not an oversight. What the single price at nume covers: consultation, prescription, the medicine, free next-working-day tracked delivery via DPD in plain unbranded packaging, and priority aftercare available every day of the week. Nothing is itemised and added on top. You can see current treatment pricing on our weight-loss treatments page; we do not print per-pen figures in copy because prices move and we want you to see the live number, not a stale one.

We do not run discount codes, promotional pricing or voucher schemes. A code offering these medicines at a steep reduction, from a seller you cannot verify on the GPhC register, is a red flag, not a bargain. The MHRA has repeatedly warned about counterfeit weight-loss pens sold online; some have contained entirely wrong substances. Verifying a pharmacy on the GPhC register before handing over payment takes about thirty seconds and is the single most useful thing you can do. Our registration number is 9012878, verifiable at that link.

For more context on what different providers include in their quoted prices, the Mounjaro price guide covers the current market without naming competitors.

For a prescription medicine, cheapest is the wrong question

The amount of tirzepatide you inject (and the clinical decisions behind that amount) require a real prescriber who has seen your health picture. If you are unsure whether your dose is appropriate, our guide on how much is too much tirzepatide explains the clinical reasoning behind dose limits and what to discuss with your prescriber. The question that actually protects you is not "who charges least?" but "who assesses me properly, sources medicine through the licensed UK supply chain, and stays responsible for my care as the dose changes?"

Our prescribers personally review every consultation the same day, a named clinician reads your answers, not software. You can read more about our clinical team's approach or browse how nume works if you want to understand the oversight behind every order. If you have specific questions before starting, our support team is available seven days a week.

When you are ready, start your free consultation and a prescriber will assess whether tirzepatide is clinically appropriate for you, including what dose would be right to begin on.