How Much Weight Should I Be Losing on Wegovy?

Step 1: Understand what the trial data actually promises

The STEP 1 trial followed nearly 2,000 adults with obesity over 68 weeks. At the 2.4mg maintenance dose of semaglutide (Wegovy), participants lost an average of roughly 15% of their starting weight. That is an average — meaning many people lost more, and some lost less. Weight loss with Wegovy is not linear either. The first weeks often produce noticeable change; progress then typically slows as the body adjusts. A plateau at month three is not unusual, and it does not necessarily mean the medicine has stopped working.

The newly approved 7.2mg dose changes the picture further. The MHRA approved the dedicated 7.2mg single-dose pen in April 2026, and trials at that dose reported around 20.7% average weight loss over 72 weeks, narrowing the gap with tirzepatide results considerably. If you want to understand how real-world Wegovy results compare to the trial figures, that context matters.

NICE's guidance on semaglutide notes that if less than 5% weight loss is achieved after six months at the maintenance dose, continuing should be reviewed. That benchmark is worth knowing, but assessing it properly requires a prescriber who can see your full picture.

Step 2: Recognise what affects your personal rate of loss

Your rate of weight loss on Wegovy depends on several factors that no headline trial figure captures. Starting weight plays a role: a 15% reduction means something quite different at 90kg than at 130kg. Dose matters too, you spend the first several months titrating upward, and the starter doses exist to help your body adjust, not to produce the full therapeutic effect. Expecting 15% loss while still on 0.5mg sets you up for unnecessary concern.

What you eat also shapes the outcome significantly. Wegovy works alongside a reduced-calorie diet, not instead of one. Our page on how much to eat on Wegovy goes into practical detail, but the short version is that appetite suppression helps, yet protein intake and hydration still need attention. Activity level, sleep quality, stress and underlying conditions all contribute too. Two people on identical doses can have meaningfully different results, and both can be responding appropriately.

If your loss feels slow, it is worth checking your weekly rate before concluding treatment is not working. Our page on what weekly loss to expect on Wegovy sets out what a typical progression looks like week by week.

Step 3: Understand what you're actually paying for, and why the price is not the main number to watch

Private Wegovy treatment in the UK is priced per pen or per month and varies between providers. Since Eli Lilly's list-price increase in September 2025 (for Mounjaro), and with Novo Nordisk's own pricing, typical private prices across providers range roughly £149 to £375 a month depending on dose and service, figures widely reported in the medical press and hedged here accordingly. What that range often does not make clear is what the headline number actually includes.

Many providers list the medicine price only. Consultation fees, prescription charges, delivery costs and any dose-review or aftercare support then appear separately. By the time you add those, the advertised figure and the real monthly cost can look quite different. It is worth asking any provider exactly what their price covers before you commit.

At nume, one price covers the consultation, the prescription, the medicine, free next-working-day tracked delivery and seven-day aftercare access. We are not the cheapest option on the market, that is a deliberate choice, not an oversight. Comparing Wegovy prices across UK providers is a reasonable thing to do; just compare like for like. Current treatment pricing is shown on our treatment page.

For a prescription medicine, the lowest price is answering the wrong question. Genuine supply through the licensed UK chain, real clinical oversight at every stage, and a prescriber who can act if your progress stalls, those are the things that determine whether treatment is worth doing at all. You can verify any online pharmacy on the GPhC register; our registration number is 9012878.

Step 4: Know when to raise a concern with your prescriber

If you have been on the maintenance dose of Wegovy for six months and have lost less than 5% of your starting weight, that is the clinical threshold at which continuing should be reassessed, per NICE's appraisal of semaglutide (TA875). That does not automatically mean stopping, but it does mean having an honest clinical conversation.

Equally, if your loss has stalled after a promising start, or if side effects are making it hard to stay on dose, those are prescriber conversations, not things to push through alone. Dose increases require clinical sign-off; they are not something to self-manage. Our aftercare team is available seven days a week precisely for moments like these, the 4pm realisation that something feels off does not have to wait until Monday morning.

For a broader sense of what to expect across a full course of treatment, our page on expected weight loss on Wegovy sets out the fuller picture. And if you're weighing up Wegovy against semaglutide more generally, the semaglutide weight loss page covers the clinical evidence for both licensed forms.