Is 2.4mg Still the Highest Dose of Wegovy Available in the UK?

Step 1: how Wegovy's titration schedule builds from 0.25mg to the new ceiling

Wegovy has always been a medicine you work up to, not one you start at full strength. The licensed schedule begins at 0.25mg weekly, then steps through 0.5mg, 1.0mg and 1.7mg before reaching what used to be the finishing line at 2.4mg. Each step takes roughly four weeks, and the reason for the slow climb is straightforward: semaglutide's most common side effects are gastrointestinal, and the gradual build gives your system time to adjust before the dose increases again.

The MHRA's January 2026 approval added a fifth rung above 2.4mg, taking the maximum to 7.2mg. Initially this was supplied as three separate 2.4mg pens used across a week. The April 2026 approval of a dedicated 7.2mg pen tidied that up into a single weekly injection, designed with a built-in covered needle that locks after use. If you want to understand how every step in the full Wegovy dose schedule works, that detail sits on its own page.

One practical point worth knowing: if you are trying to work out what the highest dose of Wegovy is and how patients reach it, 7.2mg is the current ceiling and is only appropriate for people whose BMI is 30 or above. The lower-BMI threshold used for Wegovy at the standard maintenance level does not apply to this top dose. A prescriber, not the patient, decides when and whether stepping up is clinically right.

Step 2: what the trial evidence says about outcomes at 7.2mg versus 2.4mg

The reason a higher dose matters clinically is what it does to results. At the standard 2.4mg maintenance dose, the STEP 1 trial across 68 weeks reported an average body-weight reduction of around 15%, which was already a significant advance for a once-weekly injection. The MHRA's April 2026 approval announcement for the 7.2mg pen noted that trials at this higher dose reported approximately 20.7% average weight loss over 72 weeks.

That figure starts to close the gap on tirzepatide, which produced around 20 to 21% average loss at its highest dose in the SURMOUNT-1 programme. It is a meaningful narrowing. For many people, the difference between the two medicines at their respective top doses becomes more of a clinical conversation than a clear-cut hierarchy, and a page covering what the highest mg of Wegovy means in practice sets out the milligram detail clearly if that context helps. For anyone weighing up the options, a fuller overview of Wegovy's profile covers how semaglutide works, its licence and what the evidence says across the programme as a whole.

Results quoted are trial averages. Individual outcomes vary, and no result is guaranteed. The figures are always best read alongside a conversation with a prescriber who knows your health history.

Step 3: verifying that the service prescribing for you can actually support the full dose range

Here is where the practical question often sits for people who have already started treatment elsewhere and are wondering about escalating: can your current provider support doses above 2.4mg, and are they running proper clinical reviews at each step rather than just renewing a prescription on a timer? A page looking specifically at the highest dose of Wegovy and when it becomes an option is worth reading before that conversation with a prescriber.

At nume, every repeat order is reviewed by a GPhC-registered Independent Prescriber before anything is dispensed, whether you are at 0.25mg or considering a higher dose. That review checks that the current dose is working, that side effects are manageable and that escalation is appropriate given your progress. A real clinician reads your notes; it is not automated. If you order before midday on a working day, the review happens the same day and, once approved, the pen goes out with DPD for next-working-day delivery. The story behind how we built the service explains why that clinical structure matters to us.

Specific dose availability is confirmed at consultation rather than listed here, because stock and clinical suitability both factor in. You can also find a plain cost comparison for Wegovy in the UK if price context is helpful before you start. The one thing to check for any online pharmacy is whether it appears on the GPhC register; ours does, under registration number 9012878.

Wegovy is a prescription-only medicine. The right question is not simply which dose is highest, but which dose a prescriber decides is right for you at each stage of treatment. Check your eligibility with our clinical team to start that conversation.