Mounjaro®
Starting from £179.99/mo
Start journey Learn moreEach Mounjaro KwikPen delivers its doses through a click mechanism — one full turn of the dose selector equals one week's injection, and each pen contains four clicks across its licensed schedule. Understanding how clicks correspond to doses matters practically: the wrong setting means the wrong amount. This is a prescription-only medicine, so your prescriber sets the dose; what follows explains exactly what the click markings mean and how the full titration schedule lines up.
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The Mounjaro KwikPen works differently from a standard injectable device. You do not draw up a dose or dial a number from scratch. Instead, the pen comes pre-set to dispense a fixed volume that corresponds to the strength printed on the label. When you press the injection button until you hear and feel a firm click, one full weekly dose is delivered. The pen locks after that fourth click so the fifth dose cannot accidentally be taken from an empty pen.
This is a question our prescribers hear most weeks: patients worry that they have only clicked the pen partway and not received a full dose. The rule is straightforward. One complete button-press to the stop point equals one dose. A partial or tentative press is not a half-dose, the mechanism will not release a partial volume. Either the dose goes in fully, or it does not go in at all. If there is any doubt after injecting, do not re-dose; contact your pharmacist or prescriber the same day. The NHS tirzepatide guidance advises patients to read the Patient Information Leaflet supplied with each pen for step-by-step injection instructions before their first use.
Injection technique matters too: the pen should be held firmly against the skin at a 90-degree angle for the full duration of the click, then held in place for a few further seconds before removing it. Withdrawing early is the most common reason a dose feels uncertain.
The full UK titration pathway moves through six dose levels: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. Each level has its own dedicated pen, labelled clearly on the outer packaging and on the pen body itself. You cannot turn a 2.5 mg pen into a 5 mg one by clicking differently, the concentration in the cartridge is fixed per pen.
What the click chart really shows is how many doses remain in the current pen. After injection one, the indicator window moves. After injection four, the pen is empty. A full Mounjaro dose chart maps each pen strength to its position in the schedule, so you can see at a glance which box you should be opening at week five versus week nine. The chart does not tell you when to move up, that decision belongs to your prescriber, who will consider your response, tolerability and weight trajectory.
The starting pen is always the 2.5 mg strength, and it exists specifically to let your digestive system adjust. Titration steps are typically four weeks apart, though your prescriber may hold you at a given level for longer if nausea or other gastrointestinal symptoms are significant.
Because each pen strength is a distinct product, dose-specific charts are more useful than a single generic table. If you are on the second titration step, the 5 mg click chart page shows exactly how dose one through four look in the pen window at that concentration. Patients moving into mid-range doses will find the 7.5 mg click chart covers the transition period that most people spend the longest time at. For those on higher doses, the 10 mg click chart gives the same detail for that pen.
There is also a broader reference covering how Mounjaro clicks correspond to dose levels across the schedule as a whole, which is useful if you have transferred from another provider and want to cross-check what you have been receiving. For a plain-language breakdown of what tirzepatide is and how the titration schedule is designed to work, the recommended dosage of tirzepatide page gives the clinical context behind the click numbers.
One practical note on storage: all Mounjaro pens must be kept refrigerated between 2°C and 8°C, and there is a limited window during which a pen may be kept at room temperature. The exact window is stated in the Patient Information Leaflet; never rely on a third-party summary for that figure.
Charts answer the mechanical question. They do not answer the clinical one. If you are uncertain whether it is time to increase your dose, whether a side effect justifies staying at the current level, or whether a missed injection changes your next scheduled dose, those are conversations for your prescriber rather than a click diagram.
The NICE appraisal of tirzepatide, TA1026, notes that treatment should be reviewed if less than 5% weight loss is achieved after six months at the highest tolerated dose. That kind of clinical judgement cannot come from a pen window. Knowing how to read your pen correctly is one small piece of safe use; the broader picture is built in clinical review.
If you are still working out whether Mounjaro is the right option for your situation, the Mounjaro overview page covers eligibility, how the medicine works and what private treatment involves. Cost context is covered on the Mounjaro price comparison page for anyone weighing up their options. When you are ready to speak to a prescriber, check your eligibility through a free consultation with the nume clinical team.
The people
Superintendent Pharmacist (GPhC No. 2217101)
Accountable for the safe running of our registered pharmacy, from every dispensing check to every dispatch.
Clinical Lead (GPhC No. 2231744)
Sets our clinical standards and checks everything we publish against current MHRA guidance.
Independent Prescriber (GPhC No. 2084501)
Personally reviews consultations and assesses whether treatment is clinically appropriate, and leads dose adjustments and follow-up checks.
Independent Prescriber (GPhC No. 2083426)
Personally reviews consultations and assesses whether treatment is clinically appropriate, and leads dose adjustments and follow-up checks.