Using a Wegovy Comparison Site: What the Tables Don't Tell You

Wegovy and Mounjaro are both licensed in the UK for weight management, but they work differently: Wegovy activates one gut-hormone receptor (GLP-1); Mounjaro activates two (GIP and GLP-1).
Head-to-head trial evidence exists: the SURMOUNT-5 study found tirzepatide produced greater average weight loss than semaglutide 2.4mg over 72 weeks.
Both are Prescription-Only Medicines, a qualified prescriber must assess your suitability before any supply is lawful in the UK.
As of summer 2026, a new once-daily oral Wegovy tablet (25mg maintenance dose) is also MHRA-approved, giving people who prefer not to inject a licensed alternative.

If you've landed on a Wegovy comparison site, you're probably weighing up semaglutide against another weight-loss medicine — or trying to work out which pharmacy offers the best combination of price, safety and support. The honest answer is that comparison sites can be a useful starting point, but they rarely capture what makes a meaningful difference. Wegovy (semaglutide 2.4mg injection, made by Novo Nordisk) and tirzepatide (Mounjaro) are both prescription-only medicines in the UK, meaning any legitimate provider must put a qualified prescriber between you and the medicine — and that clinical layer is the thing most comparison tools simply cannot score.

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How to Read a Wegovy Comparison Properly, and What to Check Beyond the Table

You're on a comparison site, tab open, wondering if the price difference actually matters

It's a recognisable situation. You've spotted Wegovy listed alongside Mounjaro on a comparison site, seen prices that vary by £50 or more between providers, and you're not sure what the difference really reflects. Sometimes the gap is dose-dependent: a 0.25mg starter pen costs considerably less than a 2.4mg maintenance pen, and comparison tables don't always make that clear. Sometimes it reflects what's bundled in, consultation fees, prescription charges, delivery and ongoing clinical support can all sit inside or outside the headline figure depending on the provider.

A good starting point is to ask what the quoted price includes. Any UK pharmacy supplying these medicines legally must obtain a prescription from a registered prescriber first. If a price looks unusually low and no consultation is mentioned, that's worth pausing over. The MHRA has issued clear warnings about fake weight-loss pens sold without a prescription, including counterfeit pens that have contained insulin rather than the medicine shown on the label, a serious safety risk.

For context on how Wegovy's evidence stacks up in detail, the Wegovy overview page covers the licensed indications, trial data and dosing schedule in full.

What the semaglutide comparison data actually shows

When people search for a semaglutide comparison, they usually want to know two things: how does Wegovy compare to Mounjaro on weight loss, and how does it compare to older options like Saxenda? On the first question, the SURMOUNT-5 trial (a 72-week, head-to-head study published in the New England Journal of Medicine in 2025) found that tirzepatide produced greater average weight reduction than semaglutide 2.4mg in adults with obesity who did not have diabetes. That is the most direct evidence available, and it favours Mounjaro. On the second question, the Saxenda versus Wegovy breakdown covers the differences between liraglutide and semaglutide in more detail, including their differing injection frequencies and trial results.

None of that makes Wegovy a lesser option for any given person. Individual response to these medicines varies considerably, and tolerability (how well someone manages the side-effect profile) matters as much as average trial outcomes. The right choice is a clinical one, made with a prescriber who knows your medical history. If you want to understand more about how the two semaglutide-branded products differ from each other, the page comparing Ozempic and Wegovy sets out the key distinctions in dose, licence and intended use. Comparison tables give you the map; they don't drive the car.

If you want a structured look at how the two main options sit side by side, the Wegovy vs Mounjaro comparison sets out the mechanism, trial evidence and eligibility differences without editorialising.

What a Wegovy comparison site in the UK can and can't tell you about providers

A UK-focused Wegovy comparison site will typically list private online pharmacies and clinics, sometimes with monthly prices by dose. What those listings rarely show is the clinical infrastructure behind each provider: whether consultations are reviewed by a GPhC-registered Independent Prescriber or handled by software, how quickly prescriptions are processed, whether ongoing dose reviews are included, and whether the medicines are sourced through the UK's licensed supply chain.

Those details matter. You can verify any online pharmacy on the GPhC pharmacy register before handing over personal or medical information. A legitimate pharmacy will have a GPhC premises registration number on its site. If it isn't displayed, that's reason to check carefully.

It's also worth knowing that Wegovy's price landscape shifted when Eli Lilly raised Mounjaro's UK list price in September 2025 (as widely reported at the time) which moved the two options closer together in cost at some dose points. Novo Nordisk, the company behind Wegovy, has its own list pricing structure that also shapes what pharmacies can realistically charge across different dose points. For a fuller look at how pricing actually works across providers and doses, the Wegovy price comparison page covers market context in detail. Payday timing, holiday cover and ordering cut-offs are practical things comparison tables never mention either: at nume, orders placed before 12pm Monday to Friday are dispatched the same day once clinically approved, arriving the next working day via tracked DPD delivery.

At nume, our pharmacy holds GPhC premises registration 9012878, verifiable directly at the GPhC register. Every consultation is read by a named GPhC-registered Independent Prescriber, not by an automated system. There are no subscriptions and no hidden fees: the price covers the consultation, prescription, medicine and delivery. We're not the cheapest option listed on comparison sites, that's a deliberate choice, not an oversight.

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