The Wegovy Dosage Chart: What the UK Titration Schedule Actually Looks Like

You have the box in front of you and you're not sure what dose comes next

It's one of the most common questions our prescribers hear: the pen arrived, the instructions mention a schedule, and the dosage chart for Wegovy doesn't quite match what you expected. The short answer is that the UK schedule moves through five dose levels, each lasting roughly a month, before reaching the standard maintenance dose of 2.4 mg.

Step one is 0.25 mg once weekly for four weeks. That first pen exists to help your body adjust, nausea and digestive discomfort are most noticeable when semaglutide is new to your system, and a gentler introduction reduces that. Step two raises things to 0.5 mg for another four weeks, then 1.0 mg, then 1.7 mg, and finally 2.4 mg as the ongoing maintenance level. A closer look at each individual Wegovy dose covers what changes clinically at each level if you want more detail on that.

One misconception worth naming and letting go: many people assume the lowest dose is essentially a placebo, something to push through as quickly as possible. That's not quite right. Each step is clinically considered. Skipping stages, or rushing the titration, increases the chance of side effects without proportionally speeding up results. The NHS patient information on semaglutide reflects this: the schedule is designed around tolerability, and departing from it is a conversation to have with your prescriber, not a decision to make independently.

Dose timing matters too. Injections go once a week, on the same day if possible, into the abdomen, thigh or upper arm. Rotating injection sites is standard practice. For the exact storage windows and full administration instructions, the Patient Information Leaflet that comes with your pen is the definitive reference.

The 7.2 mg dose: what the MHRA approved and who it applies to

In January 2026 the MHRA approved a 7.2 mg maintenance dose of semaglutide for weight management, initially supplied as three 2.4 mg pens used weekly. Then, on 14 April 2026, the MHRA approved a dedicated single-dose 7.2 mg pen: one pre-set weekly injection, auto-dosing mechanism, built-in covered needle that locks after use. That approval applies to adults with a BMI of 30 or above; it is not licensed for the cardiovascular indication or for BMI below 30. Trials reported an average of around 20.7% weight loss over 72 weeks at 7.2 mg, narrowing the gap with tirzepatide's highest-dose results.

The titration pathway to 7.2 mg still starts at 0.25 mg. You work through the same steps. The prescriber then makes the clinical assessment of whether 7.2 mg is appropriate for you specifically. Our dedicated page on the 2.4 mg dose covers what happens at the existing maintenance level, including the review process if loss has stalled.

A note on what doesn't belong in a Wegovy dosage chart: the 3 mg, 7 mg and 14 mg tablet strengths you might see mentioned online are Rybelsus, which is oral semaglutide licensed for type 2 diabetes. They are not steps in the Wegovy weight-loss schedule. The semaglutide dosage chart page covers that distinction in full if you've come across those figures and want clarity.

Who this titration schedule applies to, and what the prescriber is weighing up

Wegovy is licensed in the UK for adults with a BMI of 30 or above, or 27 to 29.9 with at least one weight-related health condition such as high blood pressure, type 2 diabetes or obstructive sleep apnoea. Lower BMI thresholds apply for some ethnic backgrounds under UK guidance. NICE's appraisal of semaglutide for weight management, TA875, outlines the criteria under which NHS provision is recommended, which includes specialist service involvement and a maximum treatment duration of two years.

A prescriber reviewing your case isn't just checking the BMI box. They're looking at your full medical history, any medicines you already take, and whether a particular dose step is appropriate at that moment. Someone experiencing ongoing nausea at 1.0 mg, for instance, may stay there for longer than the standard four weeks. Someone who has tolerated every step well and shown limited response might be assessed for 7.2 mg. The dosage chart sets out the possible path; the clinical review shapes the actual one. You can read about what that review involves on our about us page.

If you're considering treatment privately and want to understand what that process involves before committing, our page on Wegovy costs explains what a private prescription typically includes beyond the medicine itself. That context is worth having before you compare prices anywhere. And if you have questions about your specific situation, our team is available seven days a week.

Navigating the charts: clicks, units and the practical side of injecting

Some patients come to dosage charts not to understand the titration schedule, but to cross-check the mechanical side of injecting, specifically how many clicks correspond to each dose. Wegovy's pre-filled pens are dose-specific rather than dial-up, so each pen contains one dose and there's no click-counting involved in setting the amount. The pen is pre-set. What you're checking is that you have the right strength pen for your current prescribed stage. Our Wegovy click dosage chart page goes into the mechanics of the pen in more detail, and the clicks guide addresses the specific questions about the injection mechanism.

The Wegovy dose chart page offers a structured table view of the schedule if a visual reference is what you're after. For patients who've been given information about a 10 mg semaglutide figure and want to understand where that fits, the 10 mg semaglutide page addresses that query specifically.

If you're ready to explore whether Wegovy is appropriate for you, the right next step is a clinical conversation. Our prescribers review consultations the same day (a real clinician reads your answers, not software) and treatment is dispatched the same day it's approved for those who order before 12pm on a working day. The free consultation takes a few minutes and carries no obligation. Start your free consultation when you're ready.