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Start journey Learn moreWegovy must be kept refrigerated between 2°C and 8°C until you are ready to use it. Once removed from the fridge, a pen can be kept at room temperature — but the exact window is specified in the Patient Information Leaflet that comes with your medicine, and that leaflet is the final word, not this page. Getting storage right matters: a pen that has been exposed to heat, frozen, or kept out of the fridge beyond the permitted period should not be used. These are prescription-only medicines reviewed by a GPhC-registered prescriber before they reach you, and protecting the medicine once it arrives is the last step in keeping that clinical care intact.
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Most people store their Wegovy pen in the fridge door without thinking twice. That works well as a default, but fridge doors experience more temperature swings than the main shelf every time they open, and some fridge models run warmer at the door than the thermostat suggests. If you have any doubt, a cheap fridge thermometer settles the question in a day.
The floor of the fridge is a different hazard. Pens placed near the freezer drawer or the back wall of a small fridge can partially freeze. Frozen semaglutide should not be used: the medicine's structure can be disrupted by ice crystal formation, and there is no reliable way to tell from the outside whether damage has occurred. The semaglutide overview on our site covers the medicine's general profile, but for the specific storage limits the NHS medicines page for semaglutide is a useful reference alongside your leaflet.
Keep pens in their original carton. The cardboard is not decorative, it shields the medicine from light, which can degrade it over time. A pen left loose in a bright fridge is technically acceptable but worse than one in its box.
A question our prescribers hear most weeks is some version of: "I left my pen on the counter overnight, is it ruined?" The honest answer is: it depends on how long and at what temperature, and your Patient Information Leaflet gives the exact permitted window at room temperature. Read that document. It is specific to the product batch and formulation, and the figure can change between versions.
What the leaflet will not do is tell you what to do if you are halfway through a busy week, your pen sat in a warm kitchen for longer than permitted, and you are not sure whether to use it or replace it. In that situation, contact your prescriber. Do not simply inject and hope, semaglutide that has been heat-stressed may be less effective or, in the worst case, degraded in ways that affect tolerability. You can read more detail about what the correct temperature range for Wegovy storage looks like in practice.
One practical tip: if you take your pen out of the fridge 30 minutes before injecting to let it reach room temperature, set a timer and put it back if you decide not to inject that session. Time out of the fridge is cumulative across the pen's life.
Travelling with Wegovy takes a little planning. Airlines permit insulin and injectable medicines in hand luggage with a letter from your prescriber or pharmacist, carry the original packaging and the Patient Information Leaflet. Checked luggage holds can freeze at altitude, so your pen should stay with you in the cabin. A soft insulated cool bag with a gel ice pack (wrapped so the pen does not touch the pack directly) works for surface journeys; pharmacies sell travel cases designed for injectable medicines.
Hot climates are a particular concern. A car parked in Spanish summer sun reaches temperatures that would compromise a pen within an hour. Beach bags left in direct sunlight are no different. If you are spending extended time in a warm country, a small travel fridge or a hotel minibar is the most reliable solution.
If your trip involves a surgical procedure, there is an additional layer: your anaesthetist and surgical team need to know you are on a GLP-1 medicine, as it affects gastric emptying and anaesthetic risk. That is a separate but important conversation before any planned surgery.
For those planning travel and wanting to understand the wider storage picture for this medicine, our page on semaglutide temperature requirements covers related ground. The cost of treatment is worth knowing before you start, and our weight-loss treatment overview sets out what is involved.
There are clear situations that warrant a call rather than a best guess. Use your pen if you are confident it has stayed within the conditions your leaflet specifies. Call us if you are not. The reasons to get in touch include: a pen that was left in a warm car for several hours; a pen that appears to have frozen and thawed; a pen that looks cloudy or has visible particles (semaglutide solution should be clear and colourless); or a delivery that arrived warm because of courier delays in hot weather.
At nume, our dispensed Wegovy, which you can read more about on our dedicated treatment page, travels in DPD's tracked, temperature-appropriate packaging, but once the pen is in your hands, storage becomes your responsibility. If anything seems wrong, reach out through our contact page or the aftercare line before injecting. A wasted pen is an inconvenience. An injection of degraded medicine is a different problem.
If you are not yet on treatment and want to understand eligibility and what a clinical assessment involves, checking your eligibility with our prescribers is the right starting point. It is also worth knowing that if you overate on Wegovy and are unsure what to do next, our guidance page covers the practical steps to take.
The people
Superintendent Pharmacist (GPhC No. 2217101)
Accountable for the safe running of our registered pharmacy, from every dispensing check to every dispatch.
Clinical Lead (GPhC No. 2231744)
Sets our clinical standards and checks everything we publish against current MHRA guidance.
Independent Prescriber (GPhC No. 2084501)
Personally reviews consultations and assesses whether treatment is clinically appropriate, and leads dose adjustments and follow-up checks.
Independent Prescriber (GPhC No. 2083426)
Personally reviews consultations and assesses whether treatment is clinically appropriate, and leads dose adjustments and follow-up checks.