How to judge the best weight loss injection company — and what to look for first

You're comparing two companies side by side, here's what the price doesn't tell you

Picture the moment most people reach: two browser tabs open, two price pages, a £30 difference per month. It's tempting to close the cheaper one and click buy. But for a prescription-only medicine, that £30 gap rarely tells the full story. Some providers charge separately for the consultation, the prescription, delivery, and any clinical support call you need mid-treatment. Others fold everything in. The number on the landing page and the number on the checkout page can be quite different.

There's a practical checklist worth running before you commit. Is the pharmacy registered with the GPhC? (You can verify any online pharmacy at the GPhC pharmacy register in under a minute.) Does the site name the prescriber or clinical team? Does the consultation involve live identity and weight verification, or just a typed form? Is aftercare available once you've started treatment? These details cost the provider more to deliver, which is partly why they're missing from the cheapest listings. Our pharmacy and clinical team are transparent about exactly what's included.

One practical note: if a site offers a discount code for a prescription medicine, that's a red flag rather than a perk. Codes tied to POMs from unverified sellers are one of the signals the MHRA flags when warning about fake pens, a problem serious enough that enforcement teams seized around 20 million doses of illegally traded weight-loss medicines worth roughly £45 million in 2025.

What the two licensed medicines actually are, and why the company's supply chain matters

There are two weight-loss injections currently licensed in the UK for adults: Mounjaro (tirzepatide, made by Eli Lilly) and Wegovy (semaglutide, made by Novo Nordisk). Mounjaro activates two gut-hormone receptors, GIP and GLP-1, which together reduce appetite and slow gastric emptying. Wegovy targets the GLP-1 receptor alone. Both are subcutaneous once-weekly injections, both start at a low tolerability dose and are titrated upward by the prescriber. If you want a more detailed comparison of how they differ in practice, the guide to choosing between the injections covers the clinical picture.

The medicine has to come through the licensed UK supply chain, that means genuine pens manufactured and quality-assured for the UK market, not grey-market stock. Counterfeit tirzepatide pens were seized at an illegal UK manufacturing site as recently as October 2025. The safest indicator that a company's supply is legitimate: they source through Eli Lilly's or Novo Nordisk's authorised UK distributor relationships and will say so plainly.

A broader overview of all approved weight-loss injections available in the UK explains the licensed landscape clearly, including what Ozempic is actually licensed for (type 2 diabetes, not weight management).

The clinical infrastructure question, prescribers, not platforms

This is the part that gets glossed over most often in provider comparisons. Some services route your answers through an algorithm that auto-approves; others have a GPhC-registered Independent Prescriber read your consultation personally before anything is dispatched. The difference isn't academic. These medicines interact with other drugs, contraindicate with certain conditions, and require dose titration based on how you're tolerating them. That clinical judgement belongs to a person.

At nume, every consultation is personally reviewed by a GPhC-registered Independent Prescriber the same day. If you order before noon on a weekday, and the prescriber approves your treatment, it's dispatched that afternoon and arrives by tracked DPD the next working day in plain packaging. That 12pm cut-off is worth knowing before you plan your week around it. It's a real operational detail, not marketing copy.

Ongoing clinical review is just as important as the first approval. Dose increases, in particular, should involve evidence that the current dose is being tolerated well. A company that approves every increase automatically, without asking, is not running a clinical service, it's running a dispatch service with a prescription attached. Understanding which injection suits your situation is a decision made with a prescriber, not by a dropdown menu.

Cost context, honestly stated

Since Eli Lilly raised Mounjaro's UK list price in September 2025, private prices have ranged roughly £149 to £375 per month depending on dose and provider. That's a wide band, and it reflects genuine differences in what's included, not just margin. The full cost breakdown page sets out what drives those numbers.

nume is deliberately not the lowest price in that range. One transparent fee covers the consultation, the prescription, treatment, next-working-day DPD delivery, and 7-day aftercare. No subscription locks you in; every repeat order is clinically re-reviewed. The reviews and credentials section gives a fuller picture of what patients and regulators see when they look at our service.

The honest framing is this: for a prescription medicine, the cheapest option answers the wrong question. The question that keeps you safe is whether the supply is genuine, the prescriber is real, and the support is there when you need it. If you want to look at how providers compare across those criteria more broadly, this comparison of UK weight-loss injection companies covers the key differences. When you're ready to speak with a clinician rather than compare websites, our prescribers are the place to start.