How much weight will I lose on 1mg of Wegovy?

What 1mg actually does in the titration schedule

Wegovy's licensed dosing pathway runs 0.25mg, then 0.5mg, then 1mg, then 1.7mg, before reaching the 2.4mg maintenance dose, each step held for roughly four weeks, guided by your prescriber. The 1mg point is the midway mark, not the destination. Its job is to acclimatise your system to semaglutide's effects on gastric emptying and appetite signalling, so that when you reach 2.4mg the side-effect burden is lower. The earliest dose stage tends to produce the most modest results precisely because that is its design.

Weight loss at 1mg is real but variable. Some people notice a meaningful reduction; others see only a few pounds. The STEP 1 trial, published in the New England Journal of Medicine, reported an average of around 15% body-weight reduction over 68 weeks at 2.4mg, not at 1mg, and not within the first two months. Quoting that figure at the 1mg stage would be misleading. What the titration period does tell you is whether your body tolerates semaglutide well, which matters for everything that follows.

If you are thinking about how semaglutide performs over a longer treatment period, the full picture is more useful than any single dose snapshot. A named prescriber at nume reviews progress before every repeat, so the conversation about whether to increase is always clinical, never automatic.

Why the price question lands here, and what it actually covers

It makes sense to ask about cost at this stage. You are a month or two in, you want to know whether the spend is justified, and you have probably seen a range of prices quoted online. UK private treatment pricing for Wegovy varies by dose and provider. Since Eli Lilly's list-price increase in September 2025, market context has shifted; for semaglutide, private monthly costs typically sit in a similar range and move with the dose. The detail on what Wegovy costs through a UK private pharmacy is worth reading before you compare providers.

What headline prices frequently omit is the clinical infrastructure around the medicine: the consultation, the prescription, aftercare access, and delivery. Stripped-back pricing often means one or more of those elements carries a separate charge, added at checkout, or simply absent. That matters most at the stage you are at now, when dose-review decisions are actively in play.

nume's position is straightforward: one price covers the consultation, prescription, treatment, free next-working-day delivery, and seven-day aftercare. We lose the price-comparison table on purpose. What that buys is a prescriber who has read your notes before approving a dose change, not a system that auto-renews and ships. Current pricing is shown on the treatment page, where you can start your free consultation.

The decision: whether to continue, increase, or switch

The 1mg mark is genuinely a decision point. If you are tolerating the medicine well and seeing some response, the case for continuing to 1.7mg and then 2.4mg is straightforward, the trial evidence is strongest there. If side effects have been significant, a slower titration is a clinical option your prescriber can discuss. And if you have started to wonder whether 1mg is producing what you expected, that question deserves a direct conversation, not a search engine answer.

Switching to tirzepatide (Mounjaro) is another route some people consider at this stage; it works across two gut-hormone pathways rather than one. The Wegovy overview and the treatment comparison page cover the licensed options side by side. Neither decision (stay, titrate, or switch) should be based on cost alone.

Your 2.4mg pen will eventually sit in the fridge door like any weekly routine; getting there safely is the point of where you are now. The clinical team at nume reviews every repeat before it is dispensed, so the prescriber who approved your first supply sees your progress before the next one ships.

Why 'cheapest at this dose' is the wrong question

For a prescription medicine, the cost metric that matters is not the lowest price per pen, it is whether you are receiving genuine, licensed medicine through a regulated supply chain, reviewed by a real prescriber, with someone to contact if something changes. The MHRA has warned repeatedly about counterfeit weight-loss pens circulating through social media and unverified online sellers; checking any pharmacy on the GPhC register before you order takes under a minute and is the single most useful thing you can do. Sellers offering these medicines without a prescription, or attaching discount codes to them, are a red flag under MHRA guidance.

nume does not run discount codes or promotional pricing on prescription medicines. That is not an oversight. It reflects the view that a POM should never be marketed on price incentives. What we offer instead is speed, a clinical process that is transparent, and a prescriber team that is accountable. If you are at 1mg and weighing up whether to continue or where to continue, our FAQs cover the common questions, and our prescribers are available seven days a week.