How much weight can you lose a week on Wegovy?

You're four weeks in and the scales have barely moved, is that normal?

It happens more often than people expect. Wegovy's titration schedule starts at 0.25 mg, a dose that exists to settle the digestive system rather than drive significant weight loss. Most people see only modest changes in the first four to eight weeks. The real shift tends to come once the maintenance dose is reached and sustained. In the STEP 1 trial (68 weeks, semaglutide 2.4 mg, nearly 2,000 adults with obesity) average weight reduction was around 15%, translating to roughly 15 kg for someone starting at 100 kg. That works out at well under 0.5 kg a week when spread across the full trial period, which gives a more realistic picture than any single dramatic week. Our overview of total Wegovy weight loss breaks down what the evidence actually shows across the full duration of treatment, which is a better frame than week-by-week figures alone. Weekly Wegovy weight-loss patterns vary enormously between people and across the treatment arc, the first month rarely predicts the sixth.

What moves the needle most, beyond dose, is the lifestyle work running alongside. The trial participants also followed a reduced-calorie diet and increased physical activity. That combination is built into the licence, not optional extra advice.

How the dose you're on shapes the weekly figure

Not all Wegovy doses produce the same rate of loss, which matters when comparing prices across the titration schedule. Patients at the 0.5 mg stage will see a different weekly figure than those who have reached 2.4 mg or the newer 7.2 mg maintenance dose approved by the MHRA in January 2026. The results at 2.4 mg are the most thoroughly evidenced, but the higher dose is narrowing the gap with tirzepatide in more recent data. Those at the earlier 1 mg stage or the 0.5 mg stage are still in the titration phase, the weekly loss at those points doesn't represent what the medicine can do at full maintenance. A prescriber's job is to move patients through the schedule at a pace the body tolerates, not the fastest pace possible. Rushing titration increases side effects without improving results.

This is precisely why cheap, unsupervised access (pens sold without a clinical relationship) tends to produce worse outcomes as well as greater risk. The medicine alone isn't the treatment; the oversight is part of it. The clinical team at nume take every repeat order back to a real prescriber before it is dispensed.

What UK private pricing actually covers, and what it often doesn't

Private Wegovy prices in the UK have shifted considerably since Eli Lilly's list-price change in September 2025 moved the whole market. Reported private prices for semaglutide now typically sit in the £149–£375 range per month depending on dose and provider, though those headline figures don't always tell the full story. Many providers add separate consultation fees, prescription charges, delivery costs and aftercare charges on top. Some bundle those in. The only way to compare honestly is to establish the all-in figure before you commit.

At nume, the price you see covers the consultation, prescription, the medicine itself, and free next-working-day delivery, tracked, in plain packaging, dispatched the same day if you order before 12pm. That's the whole bill. We don't run discount codes or promotional offers on prescription medicines; the question of reduced-price Wegovy comes up often, and the honest answer is that vouchers and codes from unverified sellers are a serious safety red flag rather than a saving. The MHRA has warned repeatedly about counterfeit weight-loss pens sold online. We are not the cheapest provider, and that is a deliberate choice, the price reflects a supply chain sourced through Eli Lilly's authorised UK distributors and clinical oversight on every order. You can verify our GPhC registration at registration number 9012878 on the GPhC register. Worth checking before you order from anyone.

Why 'cheapest' is the wrong question for a prescription medicine

For a POM like Wegovy, the right questions are about the supply chain, the prescriber and the clinical process, not the per-pen price. A lower headline figure from an unverified seller means something is missing: the prescriber review, the genuine stock, or the aftercare. The MHRA seized around 20 million doses of illegally traded weight-loss medicines worth roughly £45 million in 2025 alone, including counterfeit tirzepatide pens traced to an illicit manufacturing site. Fake pens have been found to contain insulin rather than semaglutide, a potentially life-threatening substitution. Price comparison makes sense for commodities. For a medicine that changes how your appetite and metabolism work, the question is whether the clinical process is real. If you'd like to explore how Wegovy is priced near you and what different routes to access look like, our pricing page lays it out plainly. For a fuller picture of what treatment involves, our Wegovy overview is a good starting point, and the weight-loss treatment page covers all the options we offer. A free consultation through our treatment hub is the practical next step, a prescriber reviews it the same day, and there's no obligation before you decide.